Posted by
John Hughes |
Saturday, July 19, 2008
At 121 US sites, the investigators conducted two 12-week randomized, double-blind, placebo-controlled, phase 3 trials of identical design done independently in parallel, and they subjected the data to a prospectively predefined integrated analysis. Men with moderate to severe premature ejaculation who were in stable, heterosexual relationships were randomized to placebo (n = 870), 30 mg of dapoxetine (n = 874), or 60 mg of dapoxetine (n = 870) on demand (as needed, 1 - 3 hours before anticipated sexual activity). The main outcome was intravaginal ejaculatory latency time (IELT) measured by stopwatch, as well as safety and tolerability.
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